Feline Infectious Anemia (Hemobartonellosis)
By Jill Anne Sparapany
Joy with a feeding tube for eating!
Feline
infectious anemia is a significant world-wide bacterial parasitic disease that
infects red blood cells to live and reproduce. It is caused by Mycoplasma haemofelis, formerly known as
Haemobartonella felis. Cats of all
breeds and ages can be affected.
Predisposing
risk factors include any disease that causes immunosuppression, such as cancer
or FELV (feline leukemia virus), deficient vaccination status, recent history
of cat bite abscesses and exposure to fleas and ticks. Mosquito are another
transmission vector. Intact male cats may roam and be at higher risk due to
fighting behaviors.
Mycoplasma
organisms lack cell walls and depend on the host animal to survive. Since it
does not survive alone, it is a parasite dependent upon the host for survival.
It attaches to the surface of red blood cells in the bloodstream. The catās
immune system recognizes the foreign invader on the RBC surface and destruction
of the RBCās begins resulting in anemia.
Ā·
This
is different from AIHA, AutoImmune
Hemolytic Anemia, when the immune system starts to destroy healthy red blood
cells.
It is not
definitively known how the parasitic bacterium is spread from cat to cat but
the major transmission vectors are blood-sucking insects, fleas, ticks,
mosquitoes, etc. Other possible transmission routes are blood transfusions and
cat fight wounds.
Newborn
kittens may be infected but it is not known if infection is spread through
placenta, during birth or by nursing.
Clinical Signs: Signs related to
anemia.
Ā·
Pale
mucous membranes, gums
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Weakness
and lethargy
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Depression
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Weight
loss
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Loss
of appetite
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Diffuse
whole body tenderness
Ā·
Fever
Ā·
Jaundice
(yellowing of skin, eyes, mucous membranes)
Ā·
Increased
respiratory rate
Ā·
Shock
Diagnosis: By microscopic examination of the
RBCs, small dots can be seen on the blood cell surface. Depending upon the
numbers of Mycoplasma present, diagnosis can be difficult and may take several
blood smears to confirm.
Other
tests include Coombs, chemistry panel, urinalysis, FIV and FeLV testing. PCR
analysis is the best test to confirm presence of Mycoplasma haemofelis infection. PCR quantifies the amount of
mycoplasma DNA, which can be monitored for response to treatment.
Treatment: Underlying diseases or stressors must
be treated since this is an opportunistic disease affecting weakened animals.
Ā·
Antibiotics
in the tetracycline family are the treatment of choice. Tetracycline and
doxycycline. **Doxycycline may cause
esophageal strictures in cats when given in pill form ā give 1-2 teaspoons of
water after administering the pill to ensure the pill is swallowed completely.
Doxycycline is available in liquid formulation.
Ā·
Prednisone
may be given to reduce the immune systemās destruction of RBCs.
Ā·
Transfusions
may be necessary in some cats with severe anemia.
Home care and Prevention:
Ā·
Administer
medications as prescribed. If you cannot give your cat the medicine, notify
your vet! The antibiotic treatment is absolutely necessary to save your catās
life!
Ā·
Follow
recommendations by your vet for re-check appointments during recovery.
Ā·
Keep
your cat indoors to prevent exposure to vectors of infection, reduce fighting
between cats and reduce exposure to other diseases and viruses.
Ā·
Neuter
outdoor cats to reduce cat fighting.
Ā·
Use
flea and tick medications, recommended by your vet.
Prognosis: If treatment is not started in the
acute phase, up to 1/3 of all FIA cats will die. Cats who survive early stages
will become chronic carriers and may be susceptible to relapse with stress or
illness.
Comments from Alana: If your cat is an outdoor cat, has issues with fleas, is a new cat that you just got and presents with anemia, make sure your vet checks for hemobart. It may not occur to them. You have to be your cats best advocate.
Comments from Alana: If your cat is an outdoor cat, has issues with fleas, is a new cat that you just got and presents with anemia, make sure your vet checks for hemobart. It may not occur to them. You have to be your cats best advocate.
Joy loves the attention she is getting!
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